Organisms employ electrical charges and chemical reactions. And so, it stands to reason that a mage whose paradigm accepts and understands this fact could disrupt bodily functions with Forces, Matter, or both. Someone who knows little or nothing about bioelectrical impulses, on the other hand, couldn’t do the same thing until he understood that such a thing is possible; see

In theory, this sort of disruption could simply require Forces 2 (to alter electrical impulses) or Matter 2 (to change minerals or chemicals within the body). In actually, it also demands Life 3 in order to significantly impair a functioning organism. Those minerals and impulses are still part of a larger whole within a complex Pattern, and so Forces or Matter alone will not do the job.