The Sisterhood is an all-female coterie that founded a Gehenna cult as a way to lead Camarilla vampires to Set and undermine the great sect. They set out by recruiting female vampires who disliked what they saw as the glass ceiling of a male-dominated Camarilla. However, the Sisterhood’s methods have caused some degree of friction with other Setite factions. This is due to their lack of focus on Set himself, neglected in favor of an emphasis on Sekhmet. While they are ultimately still a true part of the wider Setite community, it is the path they have chosen to walk that makes some of their brethren raise an occasional eyebrow — especially when the true Dark God fades from view.

To date, only a small handful of the Sisterhood have attempted to embrace Setite Sorcery, because its practice has proven disharmonious with their doctrine. Even though Set is acknowledged as Sekhmet’s consort by the Sisterhood, the fact that magic should come from him and not from her was a point of contention. Sekhmet’s name is derived from sekhem, meaning power, so why should she not be the one providing this gift to her followers? The Sisterhood is attempting to present Sekhmet as a mask of Set to try and satisfy this controversy, but for now Setite Sorcery plays virtually no part in the workings of the Sisterhood. Once it incorporates Setite Sorcery into its operation, then relations with the wider Setite community will be considerably strengthened.